Jafari is also an associate professor of pharmaceutical sciences and is currently working at the University of California-Irvine. Jafari together with his colleagues exposed embryos and larvae of fruit flies to different doses of green tea.
Fruit flies are mostly used to study human disease owing to the fact that these fruit flies share seventy-five percent of the genes that cause diseases in humans. Their team discovered that ten milligrams of green tea actually showed a slower development of larvae. The offspring when born also showed a drastic reduction in number and size.
Female offspring that were exposed to ten milligrams of green tea showed a decrease in reproductive output and a seventeen percent decrease in lifespan.
Moreover, the researchers also found that ten milligrams of green tea also resulted to morphological abnormalities in fruit flies’ reproductive organs examples of such is atrophy in the ovaries and testicles.
Even though it was found that green tea was able to protect flies from dehydration it also found to increase their predisposition to starvation and heat stress.
Even though the study did not evaluate the mechanisms by which green tea has affected the reproduction as well as the development of fruit flies, researchers theorize that high doses of green tea could produce excessive apoptosis or programmed cell death to yield such effects.